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Dr. Harvey Risch, MD, PhD, Professor of Epidemiology Yale University.

Norm’s notes:


Early Outpatient Treatment of Symptomatic, High-Risk COVID-19 Patients That Should Be Ramped Up Immediately as Key to the Pandemic Crisis — Harvey A Risch

American Journal of Epidemiology, Volume 189, Issue 11, November 2020, Pages 1218–1226, https://doi.org/10.1093/aje/kwaa093 Published: 27 May 2020


Retraction—Hydroxychloroquine or chloroquine with or without a macrolide for treatment of COVID-19: a multinational registry analysis

Published: June 05, 2020DOI: https://doi.org/10.1016/S0140-6736(20)31324-6

[Link to the retracted paper: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)31180-6/fulltext%5D

C) Norm’s note: reference to the “Magic paper” that Dr. Risch heavily criticizes (or rather — shreds):

The Magic of Randomization versus the Myth of Real-World Evidence

List of authors.

  • Rory Collins, F.R.S., 
  • Louise Bowman, M.D., F.R.C.P., 
  • Martin Landray, Ph.D., F.R.C.P., 
  • and Richard Peto, F.R.S.



Healthcare outcomes assessed with observational study designs compared with those assessed in randomized trials

Andrew Anglemyer 1Hacsi T HorvathLisa Bero


The Environment and Disease: Association or Causation?

Austin Bradford Hill

Journal List Proc R Soc Med v.58(5); 1965 May PMC1898525

Proc R Soc Med. 1965 May; 58(5): 295–300.



Junk Studies reviewed by Dr. Risch:

Boulware et al. (University of Minnesota)

Skipper et al. (University of Minnesota)

Mitjà et al. (Catalonia RCT of individuals)

Mitjà et al. (Catalonia cluster-randomized trial)

Schwartz et al. (Alberta, Canada)


COVID-19 Studies