Hat tip and brief contextualizing comment:

Repeated vaccinations with the same antigen at short intervals ("booster shots") destabilise the immune system so that autoimmune processes occur. Among other things, antibodies against one's own DNA can be formed, as this work showed:https://t.co/HphI6PvtYl
I've warned you. pic.twitter.com/hPzmAQxQLs

— Dr John B. (@DrJohnB2) December 11, 2021

Source: PLOS ONE

Self-Organized Criticality Theory of Autoimmunity

Ken Tsumiyama, Yumi Miyazaki, Shunichi Shiozawa

December 31, 2009

Abstract

Background

The cause of autoimmunity, which is unknown, is investigated from a different angle, i.e., the defect in immune ‘system’, to explain the cause of autoimmunity.

Methodology/Principal Findings

Repeated immunization with antigen causes systemic autoimmunity in mice otherwise not prone to spontaneous autoimmune diseases. Overstimulation of CD4⁺ T cells led to the development of autoantibody-inducing CD4⁺ T (aiCD4⁺ T) cell which had undergone T cell receptor (TCR) revision and was capable of inducing autoantibodies. The aiCD4⁺ T cell was induced by de novo TCR revision but not by cross-reaction, and subsequently overstimulated CD8⁺ T cells, driving them to become antigen-specific cytotoxic T lymphocytes (CTL). These CTLs could be further matured by antigen cross-presentation, after which they caused autoimmune tissue injury akin to systemic lupus erythematosus (SLE).

Conclusions/Significance

Systemic autoimmunity appears to be the inevitable consequence of over-stimulating the host’s immune ‘system’ by repeated immunization with antigen, to the levels that surpass system’s self-organized criticality.

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Continue reading this research paper ======>Source: PLOS ONE<======